Download E-books The Chemistry and Pharmacology of TaxolВ® and its Derivatives PDF

By Vittorio Farina (Eds.)

The publication opens with a overview of the evidently happening taxoids, a cha pter which isn't a accomplished checklist of all taxoids remoted up to now , yet makes an attempt a scientific approact to describing different category es of taxoids, with specific connection with all skeletal kinds and a few of the performance styles. Biosynthetic reviews also are talk about ed, in addition to many of the simple chemistry and customary functionalities of taxoidic skeleton. Structural id of taxoids, ordinarily by way of spectroscopic ability; the formula of taxanes; the metabolism and ph armacokinetics of Taxol+ also are mentioned, as are the chemistry of t axanes relating to SAR experiences; SAR facets of the phenylisoserine facet chain; and the mode of motion of the taxanes and the mechanisms o f resistance

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